Skin sensitizers

Understanding skin sensitization

Skin sensitization refers to the process by which a substance may lead to an allergic skin reaction after repeated exposure. While not all fragrance ingredients are sensitizers, some can induce such responses in certain individuals. The fragrance industry evaluates these ingredients to determine safe use levels, aiming to minimize the risk of sensitization while allowing for the continued enjoyment of fragranced products.

Managing sensitization through science

Assessing fragrance ingredients
Fragrance ingredients undergo evaluation to determine their potential to cause skin sensitization. This involves reviewing scientific data and considering factors such as exposure levels and usage patterns. The goal is to establish guidelines that help prevent sensitization in consumers.

Quantitative Risk Assessment (QRA)
The Quantitative Risk Assessment (QRA) methodology is employed to assess the risk of skin sensitization from fragrance ingredients. This approach considers the potency of the substance, the level of exposure, and the conditions of use to determine acceptable concentrations in various product types.

Ongoing research and collaboration
The fragrance industry collaborates with scientific organizations and regulatory bodies to enhance understanding of skin sensitization. Continuous research and data collection inform updates to safety assessments and guidelines, ensuring they reflect current scientific knowledge.

10 February 2026

News

IFRA’s Matthias Vey to speak at IFRA UK seminar on skin sensitisers

Matthias Vey, Vice President of Scientific Affairs for IFRA will be speaking at the IFRA UK Sensitisers Seminar, taking place in London on 7 May 2026.