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International Dialogue for the Evaluation of Allergens

The International Dialogue on the Evaluation of Allergens (IDEA) brings scientists, dermatologists, regulators and the fragrance industry to one table, developing state-of-the-art methods that keep consumers safe from fragrance-related skin allergies

IDEA project
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A collaborative approach to allergen safety

Since 2013, IDEA has run a rolling work-plan of research, expert workshops and public reporting. Under independent supervision, it has refined quantitative risk assessment tools, promoted non-animal testing, and set transparent benchmarks that now guide safety decisions across Europe and beyond

How IDEA works

IDEA is governed by an Independent Supervisory Group of academic toxicologists who set the agenda, review progress and publish annual reports.
Through open, multi-stakeholder workshops, the project builds consensus on three pillars:

Hazard characterisation – creation of the Reference Chemical Potency List, giving agreed potency bands for 106 established fragrance allergens.

Exposure assessment – development of the refined Quantitative Risk Assessment (QRA2) model that combines consumer habits data with product-specific dermal exposure.

Validation & monitoring – Europe-wide clinical surveillance studies that track real-world trends in contact allergy and feed those findings back into safety limits.

Outputs are published free of charge, allowing authorities and companies to apply a common scientific yardstick when formulating, regulating or reformulating fragranced goods

IDEA is an established, successful multi-stakeholder initiative that propels the development of high-quality safety-assessment tools. We need reliable risk assessments based on a profound understanding of hazard and exposure.”

— Professor Jim Bridges, Chair, IDEA Supervisory Group

Latest updates about International Dialogue for the Evaluation of Allergens

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IDEA Publishes Study Supporting NAM Based QRA for Skin Sensitisation

A new article in Regulatory Toxicology and Pharmacology reports that three quantitative New Approach Methodologies (NAMs) – Regression model, SARAICE, and GARDSkin – can generate reliable points of departure for skin‑sensitisation quantitative risk assessment evaluated using the IDEA Reference Chemical Potency List.
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7th IDEA Review Meeting in Brussels to advance non-animal approaches in skin allergen risk assessment

On 29 January 2026, the International Fragrance Association (IFRA) organised the 7th Review Meeting of the International Dialogue for the Evaluation of Allergens (IDEA) in Brussels.
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IDEA workshop advances animal-free approaches to skin sensitization

Experts explore innovative methods and extended reference data to improve fragrance safety assessments
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