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New Approach Methodologies (NAMs)

Advancing fragrance safety through innovative, non-animal scientific methods that enhance precision and ethical standards in ingredient assessment.

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Modernizing safety science

New Approach Methodologies (NAMs) include innovative scientific techniques — such as in vitro assays, computational models, and high-throughput screening — that provide alternatives to traditional animal testing. These methods offer more human-relevant data, improve efficiency, and align with ethical considerations. In the fragrance industry, NAMs are integral to assessing the safety of ingredients, ensuring consumer protection while promoting scientific advancement.

Testing fragrance safety

Integrating NAMs into safety assessments
The fragrance industry incorporates NAMs to evaluate the safety of ingredients more effectively. By utilizing methods like in vitro testing and computational modeling, companies can predict potential risks with greater accuracy, reducing reliance on animal studies and expediting the assessment process.

Collaborative efforts and initiatives
Organizations within the fragrance sector collaborate with scientific bodies and regulatory agencies to develop and validate NAMs. These partnerships aim to establish standardized approaches, share data, and promote the acceptance of NAMs in regulatory frameworks globally.

Ongoing research and development
Continuous investment in research ensures that NAMs evolve to meet emerging safety assessment needs. The fragrance industry supports studies that refine existing methodologies and explore new technologies, maintaining a commitment to innovation and consumer safety.

Latest updates about New Approach Methodologies (NAMs)

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IFRA welcomes European Commission roadmap to phase out animal testing in chemical safety assessments

The International Fragrance Association (IFRA) welcomes the roadmap presented today by the European Commission to phase out animal testing for chemical safety assessments – a milestone for innovation, animal welfare, and modern, human-relevant safety science.
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IFRA contributes to EPAA report on endocrine disruption assessment using new approach methodologies

The report from the 2024 European Partnership for Alternative Approaches (EPAA) Partners’ Forum on endocrine disruption within European Union regulatory frameworks has been accepted for publication in NAM Journal.
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IFRA publishes Annual Report 2025 highlighting global engagement, regulatory progress and sustainability leadership

Geneva, 4 February 2026 – The International Fragrance Association (IFRA) has published its Annual Report 2025, marking a year defined by global connection, scientific progress and strengthened engagement with regulators, members and stakeholders worldwide.
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