Furocoumarins update

The scientific documentation supporting our second leave-on threshold of 5 ppm for furocoumarins has just been published.

Irizar, A., Boislève, F., Gautier, F., Nash, J.F., Pfuhler, S., Ritacco, G., Vey, M., Wolf, N., Cadby, P.A., 2025. Phototoxicity and skin damage: A review of adverse effects of some furocoumarins found in natural extracts. Food and Chemical Toxicology 115332.

https://www.sciencedirect.com/science/art icle/pii/S0278691525000997

Both concentration and UVA exposure are critical factors in potential skin effects.

Thresholds can be identified to effectively manage risks and ensure safe formulation.

This research is the result of collaboration within the IFRA Furocoumarin Stakeholder Group. This publication will serve as the key reference in the IFRA FC Standard.